![]() Abnormal compared to normal stress MPI (OR 11.8, 95% confidence interval 7.5 to 18.7) and stress echocardiography (OR 3.2, 95% CI 2.6 to 3.9) accurately stratified risk in patients. Seventeen studies (MPI 7, stress echocardiography 7, ETT 3) in 13,304 patients (mean age 75.5 years) were included. Summary odds ratios (ORs) between normal and abnormal test results were calculated using a random-effects model. Pooled annualized event rates were calculated for each technique. A systematic search of MEDLINE was performed for cohort studies of ≥100 patients >65 years old with ≥12 months of follow-up that reported cardiac death and/or nonfatal myocardial infarction after any of stress myocardial perfusion imaging (MPI), stress echocardiography, or exercise tolerance testing (ETT) for known or suspected coronary artery disease. Patients >65 years of age constitute a growing proportion of the population and have higher cardiovascular morbidity and mortality, but an optimal strategy to predict the risk of cardiac events in this group is unknown. doi: 10.2147/cmar.This meta-analysis evaluated the optimal noninvasive strategy for cardiac risk assessment of patients >65 years of age with known or suspected coronary artery disease using the available literature. ![]() Preoperative Fibrinogen-Albumin Ratio, Potential Prognostic Factors for Bladder Cancer Patients Undergoing Radical Cystectomy: A Two-Center Study. Robotic Assisted Radical Cystectomy vs Open Radical Cystectomy: Systematic Review and Meta-Analysis. Sathianathen NJ, Kalapara A, Frydenberg M, Lawrentschuk N, Weight CJ, Parekh D, et al. Association Between Antibiotic Treatment and the Efficacy of Intravesical BCG Therapy in Patients With High-Risk Non-Muscle Invasive Bladder Cancer. Pak S, Kim SY, Kim SH, Joung JY, Park WS, Chung J, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. It performs well on OS, CSS, and RFS, but the conclusions on DFS/PFS need to be treated with caution.īladder cancer controlling nutritional status meta-analysis prognostic factors upper tract urothelial carcinoma urothelial cancer.Ĭopyright © 2021 Peng, Du, Meng, Li, You, Li, Zhao, Cao and Li. According to different carcinoma types, cut-off value, and region, subgroup analysis of OS was performed, and similar results were obtained.īased on current evidence, this meta-analysis proves that the CONUT score of UC patients before treatment is an independent prognostic predictor. The meta-analysis results show that compared with the low CONUT group, the high CONUT group has worse over survival (OS), cancer-specific survival (CSS) and recurrence-free survival (RFS) for progression-free survival (PFS), or disease-free survival (DFS), the difference between the two groups was not statistically significant. Use STATA 16.0 and Engauge Digitizer 4.1 software for data processing and statistical analysis.Ī total of 8 studies were included in this meta-analysis. The system searches Web of Science, PubMed, MEDLINE, China National Knowledge Infrastructure (CNKI), and Cochrane Library, and the search time is up to April 2021. This meta-analysis aims to assess whether the Controlling nutritional status (CONUT) score before treatment can be an independent predictor of the prognosis of patients with urothelial cancer (UC).
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